BSRF scoliosis exome capture pathogenesis study
Researchers: tbc
Lead Institution: tbc
Duration: tbc
The BSRF is setting up the first ever scoliosis exome capture pathogenesis studyin the UK.
The purpose of the study will be to facilitate the research of adolescent idiopathic scoliosis with a view to establishing the cause or causes of the condition, and to provide better understanding of scoliosis and its management. It is intended that the study will house information for at least 2000 and up to 10,000 individuals with idiopathic scoliosis and other forms of scoliosis affecting adolescents and young adults. It will be piloted in Oxford and Manchester and rolled out to other scoliosis centres in the following months.
Genetic technology has now advanced to the point that it has become economic to scan all the genetic material from an individual (the genome) and compare this with controls without scoliosis. This makes it possible to identify many areas of the genome which may be involved in scoliosis.
The BSRF expects the prime aim of the study to be a greater understanding of the genes involved in scoliosis and some insights into mechanisms underlying scoliosis. Later these will lead to more research and ultimately new treatments.
For further information please contact: info@bsrf.co.uk or telephone:
020 8960 7110.